Mapping of RXRB to human chromosome 6p21.3

Ann Hum Genet. 1993 Jul;57(3):203-9. doi: 10.1111/j.1469-1809.1993.tb01596.x.

Abstract

Retinoid X Receptor beta (RXRB) is a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). We have confirmed the localization of RXRB to chromosome 6 and we have mapped the gene to chromosome 6p21.3-p21.1 by PCR amplification of 5' untranslated sequence in panels of rodent-human somatic cell hybrids and to 6p21.3 by fluorescent in situ hybridization.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Base Sequence
  • Chromosome Mapping
  • Chromosomes, Human, Pair 6*
  • DNA / genetics
  • DNA / isolation & purification
  • DNA Primers
  • Humans
  • Hybrid Cells
  • In Situ Hybridization, Fluorescence
  • Karyotyping
  • Molecular Sequence Data
  • Polymerase Chain Reaction / methods
  • Receptors, Cytoplasmic and Nuclear / genetics*
  • Receptors, Retinoic Acid*
  • Retinoid X Receptors
  • Retinoids / metabolism
  • Rodentia
  • Transcription Factors*

Substances

  • DNA Primers
  • Receptors, Cytoplasmic and Nuclear
  • Receptors, Retinoic Acid
  • Retinoid X Receptors
  • Retinoids
  • Transcription Factors
  • DNA

Associated data

  • GENBANK/M84820