ANCA and anti-GBM antibodies in RPGN

A K Short; V L Esnault; C M Lockwood

doi:10.1007/978-1-4757-9182-2_78

ANCA and anti-GBM antibodies in RPGN

Adv Exp Med Biol. 1993:336:441-4. doi: 10.1007/978-1-4757-9182-2_78.

Authors

A K Short¹, V L Esnault, C M Lockwood

Affiliation

¹ Department of Medicine, University of Cambridge, U.K.

PMID: 8296652
DOI: 10.1007/978-1-4757-9182-2_78

Abstract

ANCA and anti-GBM antibodies can occur together in RPGN. These patients are rare and have two distinct populations of antibodies and the ANCA specificity tends to be for myeloperoxidase more often than expected.

MeSH terms

Antibodies / blood*
Antibodies, Antineutrophil Cytoplasmic
Autoantibodies / blood*
Basement Membrane / immunology
Blotting, Western
Enzyme-Linked Immunosorbent Assay
Fluorescent Antibody Technique
Glomerulonephritis / immunology*
Humans
Immunoglobulin G / blood*
Peroxidase / immunology

Substances

Antibodies
Antibodies, Antineutrophil Cytoplasmic
Autoantibodies
Immunoglobulin G
antiglomerular basement membrane antibody
Peroxidase