Pregnancy at forty and over: a case-control study

Eur J Obstet Gynecol Reprod Biol. 1993 Mar;48(3):191-5. doi: 10.1016/0028-2243(93)90087-s.

Abstract

We compared obstetric prognosis in 327 women > or = 40 years old (148 nulliparas, 279 multiparas) with 20-30-year-old matched controls who delivered at our department between 1988 and 1990. Gestational diabetes and chronic hypertension were the only more frequent antepartum complications in cases than controls (2.4% vs. 0.3% and 3.4% vs. 0.3%, respectively). There were more premature deliveries in cases than controls (19% vs. 8%) but no difference in postdate deliveries. Cesarean section was more frequent in cases than controls in both nulliparas (64% vs. 30%) and multiparas (43% vs. 12%). Incidence of abdominal delivery for acute obstetrical indications was not increased in older gravidas. Significant differences were observed in low birthweight (17% vs. 5%) and 5-min Apgar score < 7 (8% vs. 2%). Most of the abnormal Apgar scores were recorded after cesarean section; values for vaginally-delivered infants were comparable in older and younger women. Perinatal mortality was similar in the two groups.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Age Factors
  • Apgar Score
  • Case-Control Studies
  • Cesarean Section / statistics & numerical data
  • Diabetes, Gestational / epidemiology
  • Female
  • Humans
  • Hypertension / epidemiology
  • Infant Mortality
  • Infant, Low Birth Weight
  • Infant, Newborn
  • Maternal Age*
  • Middle Aged
  • Obstetric Labor, Premature / epidemiology
  • Pregnancy
  • Pregnancy Complications / epidemiology*
  • Pregnancy Outcome*
  • Pregnancy, High-Risk*
  • Risk Factors