The complete sequence of a 19,482 bp segment located on the right arm of chromosome II from Saccharomyces cerevisiae

Yeast. 1993 Feb;9(2):189-99. doi: 10.1002/yea.320090210.

Abstract

We report here the sequence of a 19,482 bp DNA segment of chromosome II of Saccharomyces cerevisiae. The fragment contains 16 open reading frames (ORFs) covering 74% of the sequence. Four predicted products present homology with known proteins. The ORF YBR1732 exhibits a strong homology to serine hydroxymethyl transferase; the best score is 53.1% identity in 458 amino acids overlap with the serine hydroxymethyl transferase from rabbit liver. YBR1724, which shows homology with riboflavin synthase of Bacillus subtilis, is probably the RIB5 gene implied in riboflavine synthesis and mapped in this region. YBR1733 is homologous to rab protein and YBR1728 is presumably a GTPase activating protein.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Base Sequence
  • Chimerin 1
  • Chromosomes, Fungal*
  • GTP-Binding Proteins / genetics
  • Genes, Fungal / genetics*
  • Glycine Hydroxymethyltransferase / genetics
  • Molecular Sequence Data
  • Nerve Tissue Proteins / genetics
  • Oncogene Proteins / genetics
  • Open Reading Frames
  • Protein-Tyrosine Kinases*
  • Proto-Oncogene Proteins c-bcr
  • Proto-Oncogene Proteins*
  • Restriction Mapping
  • Riboflavin Synthase / genetics
  • Saccharomyces cerevisiae / genetics*
  • Sequence Analysis, DNA
  • Sequence Homology, Amino Acid

Substances

  • Chimerin 1
  • Nerve Tissue Proteins
  • Oncogene Proteins
  • Proto-Oncogene Proteins
  • Glycine Hydroxymethyltransferase
  • Riboflavin Synthase
  • Protein-Tyrosine Kinases
  • Proto-Oncogene Proteins c-bcr
  • GTP-Binding Proteins