A1F-B, a novel CCAAT-binding transcription activator that interacts with the aldolase B promoter

FEBS Lett. 1993 Apr 19;321(1):51-4. doi: 10.1016/0014-5793(93)80619-6.

Abstract

We describe here a 70 kDa transcription factor A1F-B, which preferentially binds to an element encompassing a CCAAT motif on the rat aldolase B promoter. Comparison of binding specificities, relative molecular masses, and subunit compositions with those of other known CCAAT-binding factors indicated that A1F-B is a novel member of CCAAT-binding factors.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Base Sequence
  • Binding, Competitive
  • CCAAT-Enhancer-Binding Proteins
  • DNA-Binding Proteins / metabolism*
  • Fructose-Bisphosphate Aldolase / genetics*
  • In Vitro Techniques
  • Molecular Sequence Data
  • Oligodeoxyribonucleotides / chemistry
  • Promoter Regions, Genetic*
  • Rats
  • Transcription Factors / chemistry
  • Transcription Factors / metabolism*

Substances

  • CCAAT-Enhancer-Binding Proteins
  • DNA-Binding Proteins
  • Oligodeoxyribonucleotides
  • Transcription Factors
  • Fructose-Bisphosphate Aldolase