Parapapillary chorioretinal atrophy in normal-pressure glaucoma

Am J Ophthalmol. 1993 Apr 15;115(4):501-5. doi: 10.1016/s0002-9394(14)74453-8.

Abstract

Parapapillary chorioretinal atrophy has been shown to be associated with glaucomatous optic nerve damage. We sought to determine whether eyes with normal-pressure glaucoma have an unusually large parapapillary atrophy as compared to eyes with primary open-angle glaucoma. Color stereoscopic optic disk photographs of 34 patients with normal-pressure glaucoma and 283 patients with primary open-angle glaucoma were morphometrically analyzed. Both groups were matched for neuroretinal rim area and visual field loss. Severely myopic eyes were excluded. The parapapillary atrophy was differentiated into a peripheral Zone Alpha with irregular pigmentation and a central Zone Beta with visible sclera. Zones Alpha and Beta did not differ significantly between the two groups in either frequency or size. Eyes with normal-pressure glaucoma do not have an abnormally large parapapillary atrophy as compared to eyes with primary open-angle glaucoma, which is diagnostically and pathogenetically important.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Atrophy
  • Choroid / pathology*
  • Female
  • Glaucoma / pathology*
  • Glaucoma / physiopathology
  • Glaucoma, Open-Angle / pathology*
  • Glaucoma, Open-Angle / physiopathology
  • Humans
  • Intraocular Pressure*
  • Male
  • Middle Aged
  • Optic Disk / pathology*
  • Random Allocation
  • Retina / pathology*