MHC expression of African green monkeys of Barbados is limited in heterogeneity

J Med Primatol. 1995 Feb;24(2):81-6. doi: 10.1111/j.1600-0684.1995.tb00150.x.

Abstract

Major histocompatibility complex expression of activated peripheral blood lymphocytes of captive African green monkeys from Barbados and from Africa were analyzed biochemically; class I molecules by one-dimensional isoelectric focusing and class II DR molecules by one-dimensional nonequilibrium pH gradient electrophoresis. Much less diversity was observed in the major histocompatability molecule expression of the African green monkeys of Barbados than in the African cohort.

Publication types

  • Comparative Study

MeSH terms

  • Africa
  • Animals
  • Barbados
  • Chlorocebus aethiops / immunology*
  • Gene Expression
  • Genetic Variation
  • Geography
  • HLA-DR Antigens / analysis
  • HLA-DR Antigens / biosynthesis
  • HLA-DR Antigens / isolation & purification
  • Histocompatibility Antigens Class I / analysis
  • Histocompatibility Antigens Class I / biosynthesis*
  • Histocompatibility Antigens Class I / isolation & purification
  • Histocompatibility Antigens Class II / analysis
  • Histocompatibility Antigens Class II / biosynthesis*
  • Histocompatibility Antigens Class II / isolation & purification
  • Isoelectric Focusing
  • Lymphocyte Activation
  • Lymphocytes / immunology
  • Major Histocompatibility Complex*

Substances

  • HLA-DR Antigens
  • Histocompatibility Antigens Class I
  • Histocompatibility Antigens Class II