Ultrastructural study of the coagulating gland of Wistar rats submitted to experimental chronic alcohol ingestion

Prostate. 1996 Jun;28(6):341-6. doi: 10.1002/(SICI)1097-0045(199606)28:6<341::AID-PROS1>3.0.CO;2-D.

Abstract

Morphological changes of coagulating gland of Wistar rats submitted to the experimental chronic alcoholism were noted. Ultrastructurally, it was observed reduction of the granular endoplasmic reticulum cisternae and nuclei with basal position and irregular shape. The epithelial cells presented pycnotic nuclei and the mitochondrial cristae disappeared, characteristic of cellular degeneration.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cell Nucleus / drug effects
  • Cell Nucleus / ultrastructure
  • Endoplasmic Reticulum, Rough / drug effects
  • Endoplasmic Reticulum, Rough / ultrastructure
  • Epithelial Cells
  • Epithelium / drug effects
  • Epithelium / ultrastructure
  • Ethanol / toxicity*
  • Genitalia, Male / cytology
  • Genitalia, Male / drug effects
  • Genitalia, Male / ultrastructure*
  • Male
  • Microscopy, Electron
  • Mitochondria / drug effects
  • Mitochondria / ultrastructure
  • Rats
  • Rats, Wistar

Substances

  • Ethanol