Variant translocation t(6;10)(p21;q22) in pulmonary chondroid hamartoma

F Minoletti; G Sozzi; C Calderone; S Di Palma; S Pilotti; A Azzarelli; M A Pierotti

doi:10.1002/(SICI)1098-2264(199604)15:4<246::AID-GCC6>3.0.CO;2-1

Variant translocation t(6;10)(p21;q22) in pulmonary chondroid hamartoma

Genes Chromosomes Cancer. 1996 Apr;15(4):246-8. doi: 10.1002/(SICI)1098-2264(199604)15:4<246::AID-GCC6>3.0.CO;2-1.

Authors

F Minoletti¹, G Sozzi, C Calderone, S Di Palma, S Pilotti, A Azzarelli, M A Pierotti

Affiliation

¹ Division of Experimental Oncology A, Istituto Nazionale Tumori, Milan, Italy.

PMID: 8703850
DOI: 10.1002/(SICI)1098-2264(199604)15:4<246::AID-GCC6>3.0.CO;2-1

Abstract

Banding cytogenetics and fluorescence in situ hybridization analysis of a pulmonary chondroid hamartoma (PHC) showed the presence of a t(6;10)(p21;q22). A cytogenetically identical translocation has previously been found in another case of PHC, suggesting that it could represent a variant form of the standard t(6;14)(p21;q24).

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Chromosome Banding
Chromosomes, Human, Pair 10*
Chromosomes, Human, Pair 6*
Hamartoma / genetics*
Humans
In Situ Hybridization, Fluorescence
Karyotyping
Lung / abnormalities*
Translocation, Genetic*