Population study of the STRs HUMTH01 (including a new variant) and HUMVWA31A in Catalonia (northeast Spain)

Int J Legal Med. 1996;108(6):318-20. doi: 10.1007/BF02432128.

Abstract

Allele and genotype frequencies for 2 short tandem repeat loci were determined in a population sample from Catalonia (Spain) using the polymerase chain reaction. After denaturing PAG electrophoresis, seven common and one variant (13.3) alleles were identified for HUMTH01 in a sample of 234 unrelated individuals, and seven alleles were found for HUMVWA31A in 162 individuals. No deviation from Hardy-Weinberg equilibrium was found. The observed heterozygosities are 76.92 and 79.62 respectively. The discrimination power determined for the individual loci is 0.928 and 0.937 respectively.

MeSH terms

  • Alleles
  • Antigens / genetics*
  • Chromosome Mapping
  • DNA / genetics*
  • Gene Frequency / genetics
  • Genetic Carrier Screening
  • Genetic Variation / genetics*
  • Genetics, Population*
  • Humans
  • Polymerase Chain Reaction
  • Polymorphism, Genetic / genetics*
  • Repetitive Sequences, Nucleic Acid / genetics*
  • Spain
  • von Willebrand Factor / immunology

Substances

  • Antigens
  • Von Willebrand antigen
  • von Willebrand Factor
  • DNA