Intrinsic and acquired resistance to methotrexate in acute leukemia

N Engl J Med. 1996 Oct 3;335(14):1041-8. doi: 10.1056/NEJM199610033351408.

Authors

R Gorlick¹, E Goker, T Trippett, M Waltham, D Banerjee, J R Bertino

Affiliation

¹ Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

PMID: 8793930
DOI: 10.1056/NEJM199610033351408

No abstract available

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Acute Disease
Drug Resistance / genetics
Genes, Tumor Suppressor
Humans
Leukemia / drug therapy*
Methotrexate / chemistry
Methotrexate / metabolism
Methotrexate / therapeutic use*

Substances

Methotrexate