The ubiquitin-mediated proteolytic system: involvement of molecular chaperones, degradation of oncoproteins, and activation of transcriptional regulators

Cold Spring Harb Symp Quant Biol. 1995:60:491-501. doi: 10.1101/sqb.1995.060.01.053.

Authors

A Ciechanover¹, A Laszlo, B Bercovich, I Stancovski, I Alkalay, Y Ben-Neriah, A Orian

Affiliation

¹ The Department of Biochemistry, Faculty of Medicine, Technion-Israel Institute of Technology, Haifa.

PMID: 8824422
DOI: 10.1101/sqb.1995.060.01.053

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Carrier Proteins / metabolism
DNA-Binding Proteins / metabolism
Endopeptidases / metabolism*
HSC70 Heat-Shock Proteins
HSP70 Heat-Shock Proteins*
I-kappa B Proteins*
In Vitro Techniques
Models, Biological
Molecular Chaperones / metabolism*
NF-KappaB Inhibitor alpha
NF-kappa B / metabolism
Oncogene Proteins / metabolism*
Proto-Oncogene Proteins c-fos / metabolism
Proto-Oncogene Proteins c-jun / metabolism
Rabbits
Reticulocytes / metabolism
Transcriptional Activation
Ubiquitins / metabolism*

Substances

Carrier Proteins
DNA-Binding Proteins
HSC70 Heat-Shock Proteins
HSP70 Heat-Shock Proteins
I-kappa B Proteins
Molecular Chaperones
NF-kappa B
Oncogene Proteins
Proto-Oncogene Proteins c-fos
Proto-Oncogene Proteins c-jun
Ubiquitins
NF-KappaB Inhibitor alpha
Endopeptidases