Tubercidin analogs from the ascidian Didemnum voeltzkowi

J Nat Prod. 1996 Oct;59(10):1000-1. doi: 10.1021/np960457f.

Abstract

Two new 5'-deoxypyrrolo[2,3-d]pyrimidine (7-deazapurine) nucleosides, 5'-deoxytubercidin and 5'-deoxy-3-bromotubercidin, were identified from the ascidian Didemnum voeltzkowi. Two known anomers of 5'-deoxy-3-iodotubercidin were also purified from the extract. Assignments were made on the basis of 1H and 13C chemical shifts as well as HPLC-MS experiments.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Chromatography, High Pressure Liquid
  • Magnetic Resonance Spectroscopy
  • Nucleosides / chemistry
  • Nucleosides / isolation & purification
  • Spectrometry, Mass, Fast Atom Bombardment
  • Tubercidin / analogs & derivatives*
  • Tubercidin / isolation & purification*
  • Urochordata / chemistry*

Substances

  • Nucleosides
  • Tubercidin