The effects of a selective inhibitor of tryptophan 2,3-dioxygenase and a combined inhibitor of tryptophan 2,3-dioxygenase and 5-HT reuptake on serotonergic function in the rat

Adv Exp Med Biol. 1996:398:61-5. doi: 10.1007/978-1-4613-0381-7_7.
No abstract available

MeSH terms

  • Animals
  • Brain / drug effects
  • Brain / physiology*
  • Enzyme Inhibitors / pharmacology
  • Fluoxetine / pharmacology
  • Indoles / pharmacology*
  • Kinetics
  • Pargyline / pharmacology
  • Pyridines / pharmacology*
  • Raphe Nuclei / drug effects
  • Raphe Nuclei / physiology*
  • Rats
  • Selective Serotonin Reuptake Inhibitors / pharmacology*
  • Serotonin / metabolism*
  • Tryptophan / metabolism*
  • Tryptophan / pharmacology
  • Tryptophan Oxygenase / antagonists & inhibitors*

Substances

  • Enzyme Inhibitors
  • Indoles
  • Pyridines
  • Serotonin Uptake Inhibitors
  • TDO inhibitor LM10
  • Fluoxetine
  • 709W92
  • Serotonin
  • Tryptophan
  • Pargyline
  • Tryptophan Oxygenase