Reassignment of the 92-kDa type IV collagenase gene (CLG4B) to human chromosome 20

Cytogenet Cell Genet. 1996;72(2-3):159-61. doi: 10.1159/000134175.

Abstract

The collagenase type IV B gene (CLG4B) was previously mapped to human chromosome 16 by hybridization of a cDNA probe to DNAs from a somatic cell hybrid panel. We have relocalized CLG4B to chromosome 20 based on three different lines of evidence: screening a somatic cell hybrid mapping panel, fluorescence in situ hybridization (FISH), and linkage analysis using a newly identified polymorphism.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Base Sequence
  • Chromosomes, Human, Pair 20 / genetics*
  • Collagenases / genetics*
  • Genetic Linkage
  • Humans
  • In Situ Hybridization, Fluorescence
  • Molecular Sequence Data
  • Polymerase Chain Reaction

Substances

  • Collagenases