Clinical and epidemiological analysis of Lyme disease cases treated at the Infectious Diseases Clinic of the Medical University of Gdańsk and the District Hospital of Infectious Diseases in the years 1993-1995 was done. The results were compared to data presented in the literature. The material consisted of 184 patients, 169 in I stage of the disease and 15 in the II stage. Out of 15 in the II stage, 2 patients presented with lymphocytoma benigna cutis, 7 with arthritis and 6 with neuroboreliosis. The Lyme disease diagnosis was confirmed with positive serological tests in 45% of patients in the I stage and in 100% of patients in the II stage. Over the analysed time interval, 1993-1995, the incidence of Lyme disease has increased markedly; 1993-38 cases, 1994-50 cases and 96 cases in 1995.