Obsessive-compulsive disorder in patients with schizophrenia or schizoaffective disorder

Am J Psychiatry. 1997 Feb;154(2):271-3. doi: 10.1176/ajp.154.2.271.

Abstract

Objective: The authors evaluated the frequency of DSM-III-R obsessive-compulsive disorder in patients with a primary diagnosis of schizophrenia or schizoaffective disorder.

Method: Patients with schizophrenia (N = 52) or schizoaffective disorder (N = 25) were evaluated for the presence of obsessions and compulsions by means of the Structured Clinical Interview for DSM-III-R, the Yale-Brown Obsessive Compulsive Scale, chart review, and contact with the treating clinicians.

Results: Six (7.8%) of the 77 patients met the DSM-III-R criteria for both obsessive-compulsive disorder and schizophrenia or schizoaffective disorder.

Conclusions: These findings suggest that obsessive-compulsive disorder occurs in a substantial percentage of patients with schizophrenia or schizoaffective disorder. The addition of medications targeted at obsessive-compulsive disorder may be beneficial to these patients but requires systematic evaluation.

MeSH terms

  • Adult
  • Comorbidity
  • Confidence Intervals
  • Female
  • Humans
  • Male
  • Middle Aged
  • Obsessive-Compulsive Disorder / diagnosis
  • Obsessive-Compulsive Disorder / epidemiology*
  • Psychiatric Status Rating Scales
  • Psychotic Disorders / diagnosis
  • Psychotic Disorders / epidemiology*
  • Schizophrenia / diagnosis
  • Schizophrenia / epidemiology*