An in vitro immersion bioassay was used to compare the efficacy of selected pyrethroids against a deltamethrin-resistant strain of rabbit ear mite (Psoroptes cuniculi). A lack of cross-resistance between bromo (deltamethrin) and chloro analogues (cypermethrin) of alpha-cyano-3-phenoxybenzyl-dihalovinyl-dimethylcyclopropane carboxylate was detected. Whereas deltamethrin proved to be inactive (48-h mortality 21.9% at 1000 mg/kg), each cypermethrin isomer mixture tested, including alpha-cypermethrin [IR(cis) alpha S + 1 S (cis) alpha R] and theta-cypermethrin [1R(trans) alpha S + 1 S (trans) alpha R] and their mixture at a ratio of 4/6, beta-cypermethrin, showed high efficiency (48-h mortality > or = 95% at 1000 mg/kg).