Abstract
The impact of guiding catheter selection on the measurement of coronary flow reserve was assessed by injecting increasing doses of adenosine through 3 different catheters often used during coronary interventions. When guiding catheters with side holes were used, an approximate doubling of the adenosine dose was required to produce a coronary flow reserve response similar to a 12-micrograms dose of adenosine injected through guiding catheters without side holes.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Adenosine / administration & dosage
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Adenosine / pharmacology
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Analysis of Variance
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Animals
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Blood Flow Velocity / drug effects
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Blood Pressure / drug effects
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Cardiac Catheterization / instrumentation*
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Catheterization / instrumentation*
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Coronary Circulation* / drug effects
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Coronary Vessels / drug effects
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Equipment Design
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Heart Rate / drug effects
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Surface Properties
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Swine
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Vasodilator Agents / administration & dosage
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Vasodilator Agents / pharmacology
Substances
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Vasodilator Agents
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Adenosine