Is HTLV-1 status another antenatal screening test that we need?

Br J Obstet Gynaecol. 1997 Feb;104(2):258-60. doi: 10.1111/j.1471-0528.1997.tb11057.x.

Abstract

Human T-lymphocytic virus type 1 (HTLV-1) carriage is associated with a 2% to 5% lifetime risk of developing a severe, if not fatal, disease. In our Inner London antenatal population, we found that the carrier rate was 0.3%. The antenatal transmission rate is known to be very low, but if the infant is breastfed the transmission rate is up to 25%. It is therefore possible to interrupt the transmission cycle by advising against breastfeeding. The ethical and fiscal issues surrounding antenatal testing are addressed.

MeSH terms

  • Enzyme-Linked Immunosorbent Assay
  • Female
  • HTLV-I Infections / diagnosis*
  • HTLV-I Infections / epidemiology
  • Humans
  • London / epidemiology
  • Pregnancy
  • Prenatal Diagnosis*
  • Prevalence