Previous research has shown that patients who are satisfied with their interactions with a health provider tend to adhere to treatment. This study sets out to investigate the quality of the communication in the interactions between clinic nurses at a Western Cape clinic and newly notified tuberculosis patients. Routine interviews between clinic nurses and tuberculosis patients were video-recorded, transcribed and analysed, using a qualitative instrument devised by the researchers. The interactions were evaluated as being essentially nurse-centred; there was an unequal distribution of control, poor receptivity to the patient and little confirmation of the patient. The nursing staff received a period of training in communication skills. After this training their interviews with patients revealed a significant shift towards a more patient-centred approach, resulting in mutual satisfaction of nurse and patient. Training in communication skills should be introduced at TB clinics, in order to improve patients' adherence to therapy.