Abstract
The present study provides evidence that interleukin (IL)-6 and IL-8 are the main endogenous mediators of acute phase response in patients with myocardial infarction. This conclusion was supported by the observation of a strict relation between IL-6 elevation and the extent of myocardial tissue damage and rise in body temperature.
MeSH terms
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Acute-Phase Reaction / blood
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Acute-Phase Reaction / physiopathology*
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Adult
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Aged
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Aged, 80 and over
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Female
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Humans
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Inflammation Mediators / blood
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Inflammation Mediators / physiology*
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Interleukin-6 / blood
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Interleukin-6 / physiology*
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Interleukin-8 / blood
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Interleukin-8 / physiology*
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Male
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Middle Aged
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Myocardial Infarction / blood
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Myocardial Infarction / drug therapy
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Myocardial Infarction / physiopathology*
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Thrombolytic Therapy
Substances
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Inflammation Mediators
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Interleukin-6
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Interleukin-8