Evidence that suppression of IL-1 induced collagenase mRNA expression by dihomo-gamma-linolenic acid (DGLA) involves inhibition of NF kappa B binding

Inflamm Res. 1997 Aug:46 Suppl 2:S177-8. doi: 10.1007/s000110050168.
No abstract available

MeSH terms

  • 8,11,14-Eicosatrienoic Acid / pharmacology*
  • Cells, Cultured
  • Collagenases / genetics*
  • DNA / metabolism
  • Gene Expression / drug effects*
  • Humans
  • Interleukin-1 / pharmacology*
  • NF-kappa B / antagonists & inhibitors*
  • NF-kappa B / metabolism
  • Promoter Regions, Genetic
  • RNA, Messenger / biosynthesis*

Substances

  • Interleukin-1
  • NF-kappa B
  • RNA, Messenger
  • DNA
  • Collagenases
  • 8,11,14-Eicosatrienoic Acid