A retrospective survey of 1456 cataract operations done at one hospital from 1991 to 1994 found three cases of chronic pseudophakic endophthalmitis. In two of these cases and one referred from another center, microbiological studies from aqueous humor, capsular bag, and vitreous humor were performed using an identical technique. The histopathology in the three cases showed the presence of microorganisms in the capsular wall, although the cultures were only positive in one case (for corynebacterium species).