The aim of the study is an analysis of the complications among the patients who underwent endoscopic sphincterotomy. In years 1991-1996 in our Department 412 patients underwent endoscopic sphincterotomy. Bile ducts stones, acute bile pancreatitis, papilla Vateri stricture and the postoperative bile fistula were the indications for the procedure. Complications occurred in 37 patients (12 of them were operated on). One patient died due to duodenal perforation. GI bleeding, acute pancreatitis, common bile duct perforation, recurrence of the stricture and missing the concrement in the duct were the main complications. Endoscopic sphincterotomy remains the recommended method in describe cases.