Recently, an Er:YAG laser has attracted attention because of the possibility of cutting hard tissues with extremely small thermal effects. In this article, we report 8 cases (13 teeth) of apicoectomy using Er:YAG laser. All procedures were performed without using an air turbine or an electric drill. Although the cutting speed of this laser was slightly slower than ordinary methods, its clinical application for apicoectomy has many advantages including absence of discomfort and vibration, less chance for contamination of the surgical site, and reduced risk of trauma to adjacent tissue.