Polyketomycin, a new antibiotic from Streptomyces sp. MK277-AF1. II. Structure determination

I Momose; W Chen; H Nakamura; H Naganawa; H Iinuma; T Takeuchi

doi:10.7164/antibiotics.51.26

Polyketomycin, a new antibiotic from Streptomyces sp. MK277-AF1. II. Structure determination

J Antibiot (Tokyo). 1998 Jan;51(1):26-32. doi: 10.7164/antibiotics.51.26.

Authors

I Momose¹, W Chen, H Nakamura, H Naganawa, H Iinuma, T Takeuchi

Affiliation

¹ Institute of Microbial Chemistry, Tokyo, Japan.

PMID: 9531984
DOI: 10.7164/antibiotics.51.26

Abstract

A new antibiotic, polyketomycin, was isolated from the culture broth of Streptomyces sp. MK277-AF1. The structure was determined by various NMR spectroscopies, X-ray crystallographic analysis and degradation experiments.

MeSH terms

Anti-Bacterial Agents / chemistry*
Glyoxylates / chemistry*
Magnetic Resonance Spectroscopy
Streptomyces / chemistry*

Substances

Anti-Bacterial Agents
Glyoxylates
polyketomycin