Two new cases of near-tetraploidy in adult acute myeloid leukemia

B Espinet; F Solé; S Woessner; L Florensa; C Besses; J Sans-Sabrafen

doi:10.1016/s0165-4608(97)00315-4

Two new cases of near-tetraploidy in adult acute myeloid leukemia

Cancer Genet Cytogenet. 1998 Apr 15;102(2):131-4. doi: 10.1016/s0165-4608(97)00315-4.

Authors

B Espinet¹, F Solé, S Woessner, L Florensa, C Besses, J Sans-Sabrafen

Affiliation

¹ Laboratori de Citologia Hematològica, Hospital Central l'Aliança, Barcelona, Spain.

PMID: 9546065
DOI: 10.1016/s0165-4608(97)00315-4

Abstract

Tetraploid or near-tetraploid karyotype has been described rarely in hematologic neoplasms. Herein we report two new cases of adult acute myeloblastic leukemia, M0 and M1 FAB subtypes that showed near-tetraploid clones that were studied with conventional cytogenetics and in situ hybridization (ISH). We compare our new cases with those previously reported.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Aged
Aged, 80 and over
Aneuploidy*
Humans
Immunophenotyping
In Situ Hybridization
Karyotyping
Leukemia, Myeloid, Acute / genetics*
Male
Middle Aged