Construction of recombinant vaccinia virus expressing Rinderpest Virus nucleocapsid protein and its immunogenicity in mice

J Vet Med Sci. 1998 May;60(5):655-6. doi: 10.1292/jvms.60.655.

Abstract

Recombinant vaccinia virus (rVV) was constructed by inserting Rinderpest Virus (RPV) nucleocapsid (N) protein gene. The rVV expressed RPV-N protein in the rVV-infected cells. The rVV was shown to produce RPV-N-specific antibody in mice.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antibodies, Viral / biosynthesis
  • Antibody Formation
  • Enzyme-Linked Immunosorbent Assay
  • Mice
  • Mice, Inbred BALB C
  • Nucleocapsid / immunology*
  • Rinderpest / immunology*
  • Rinderpest / prevention & control
  • Rinderpest virus / immunology*
  • Vaccines, Synthetic*
  • Vaccinia virus / immunology*
  • Viral Vaccines*

Substances

  • Antibodies, Viral
  • Vaccines, Synthetic
  • Viral Vaccines