Background: Data is reported from an ongoing trial considering whether visual loss associated with migraine is consistent with a selective deficit in M- or P-cell functioning.
Methods: The psychophysical tests used include spatio-temporal contrast thresholds and luminance increment thresholds for a spot drifting across a spatially or temporally modulated background. A migraineur and 15 non-headache controls participated in the present study. Measurements were made foveally and at 10 degrees in the superior field. Static and flicker perimetry were conducted.
Result/conclusion: Regionalized losses occurred for stimuli with moderate temporal frequencies (16 Hz), which is consistent with M-cell dysfunction.