Multiresidue supercritical fluid extraction method for the recovery at low ppb levels of three sulfonamides from fortified chicken liver

R J Maxwell; A R Lightfield

doi:10.1016/s0378-4347(98)00277-1

Multiresidue supercritical fluid extraction method for the recovery at low ppb levels of three sulfonamides from fortified chicken liver

J Chromatogr B Biomed Sci Appl. 1998 Sep 18;715(2):431-5. doi: 10.1016/s0378-4347(98)00277-1.

Authors

R J Maxwell¹, A R Lightfield

Affiliation

¹ U.S. Department of Agriculture, Agricultural Research Service, Eastern Regional Research Center, Wyndmoor, PA 19038, USA.

PMID: 9792530
DOI: 10.1016/s0378-4347(98)00277-1

Abstract

A supercritical fluid extraction (SFE) method is proposed for the recovery of three sulfonamides from chicken liver. Samples were extracted at 680 bar and 40 degrees C using unmodified carbon dioxide and were collected free of co-extracted artifactual material on an in-line neutral alumina sorbent bed. High recoveries of sulfamethazine (SMZ), sulfadimethoxine (SDM) and sulfaquinoxaline (SQX) were obtained from chicken liver samples fortified at levels from 1000 to 50 ppm.

Publication types

Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Animals
Chickens
Chromatography / methods*
Liver / chemistry*
Sensitivity and Specificity
Spectrophotometry, Ultraviolet
Sulfadimethoxine / analysis*
Sulfamethazine / analysis*
Sulfaquinoxaline / analysis*

Substances

Sulfadimethoxine
Sulfamethazine
Sulfaquinoxaline