Anticytomegalovirus (anti-CMV) immunoglobulin G avidity in identification of pregnant women at risk of transmitting congenital CMV infection

Clin Diagn Lab Immunol. 1999 Jan;6(1):127-9. doi: 10.1128/CDLI.6.1.127-129.1999.

Abstract

In this work, we show that the determination of the anticytomegalovirus antibody avidity carried out before week 18 of gestation is a helpful tool to identify women for enrollment in prenatal diagnosis. This procedure can identify all pregnant women who will give birth to an infected newborn.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amniotic Fluid / virology
  • Antibodies, Viral / blood*
  • Antibody Affinity
  • Case-Control Studies
  • Cytomegalovirus / immunology*
  • Cytomegalovirus / isolation & purification
  • Cytomegalovirus Infections / complications
  • Cytomegalovirus Infections / congenital*
  • Cytomegalovirus Infections / transmission*
  • Female
  • Gestational Age
  • Humans
  • Immunoglobulin G / blood
  • Infant, Newborn
  • Infectious Disease Transmission, Vertical
  • Pregnancy
  • Pregnancy Complications, Infectious / diagnosis
  • Pregnancy Complications, Infectious / immunology*
  • Prenatal Diagnosis
  • Risk Factors

Substances

  • Antibodies, Viral
  • Immunoglobulin G