[Knockout mice: advantages and limitations for biological modeling. Definitions, principles and examples]

MeSH terms

• Animals
• Chimera / genetics
• DNA, Recombinant / genetics
• Disease Models, Animal*
• Gene Transfer Techniques
• Humans
• Immunity, Cellular / genetics
• Mice
• Mice, Knockout / genetics*
• Mutagenesis / genetics
• Oncogenes / genetics
• Stem Cells / physiology