Alternative splicing, genomic structure, and fine chromosome localization of REV3L

Cytogenet Cell Genet. 1998;83(1-2):18-20. doi: 10.1159/000015157.

Abstract

We have localized a human homolog, REV3L, of the Saccharomyces cerevisiae REV3 gene on chromosome region 6q21. The full-length cDNA consists of 10,919 nucleotides, with a putative open reading frame of 9,159 bp for a predicted protein of 3,053 amino acids. The gene contains 33 exons in about 200 kb of genomic DNA. In contrast to the previously reported sequence, an additional exon and an alternative splicing site are demonstrated.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alternative Splicing*
  • Chromosome Mapping
  • Chromosomes, Human, Pair 6*
  • DNA Primers
  • DNA, Complementary
  • DNA-Directed DNA Polymerase / genetics*
  • Exons
  • Fungal Proteins / genetics*
  • Genome, Fungal
  • Genome, Human*
  • Humans
  • Introns
  • Polymorphism, Genetic
  • Saccharomyces cerevisiae / enzymology
  • Saccharomyces cerevisiae / genetics
  • Saccharomyces cerevisiae Proteins*

Substances

  • DNA Primers
  • DNA, Complementary
  • Fungal Proteins
  • Saccharomyces cerevisiae Proteins
  • DNA-Directed DNA Polymerase
  • REV3 protein, S cerevisiae