Activation and methotrexate-mediated suppression of the TNF alpha promoter in T cells and macrophages

Ann N Y Acad Sci. 1998 Nov 17:859:219-22. doi: 10.1111/j.1749-6632.1998.tb11133.x.
No abstract available

MeSH terms

  • CD4-Positive T-Lymphocytes / immunology
  • Cell Line
  • Cells, Cultured
  • Gene Expression Regulation / drug effects
  • Gene Expression Regulation / immunology*
  • Humans
  • Macrophages / drug effects
  • Macrophages / immunology*
  • Methotrexate / pharmacology*
  • Recombinant Fusion Proteins / biosynthesis
  • T-Lymphocytes / drug effects
  • T-Lymphocytes / immunology*
  • Transfection
  • Tumor Necrosis Factor-alpha / biosynthesis
  • Tumor Necrosis Factor-alpha / genetics*

Substances

  • Recombinant Fusion Proteins
  • Tumor Necrosis Factor-alpha
  • Methotrexate