The Jun kinase 2 isoform is preferentially required for epidermal growth factor-induced transformation of human A549 lung carcinoma cells.
Bost F, McKay R, Bost M, Potapova O, Dean NM, Mercola D.
Bost F, et al. Among authors: mckay r.
Mol Cell Biol. 1999 Mar;19(3):1938-49. doi: 10.1128/MCB.19.3.1938.
Mol Cell Biol. 1999.
PMID: 10022881
Free PMC article.
As observed here, EGF treatment also greatly enhances the tumorigenicity of A549 cells, suggesting an important role for JNK in cancer cell growth (F. Bost, R. McKay, N. Dean, and D. Mercola, J. Biol. Chem. 272:33422-33429, 1997). Several isoforms families of JNK, J …
As observed here, EGF treatment also greatly enhances the tumorigenicity of A549 cells, suggesting an important role for JNK in cancer cell …