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A typical bacterial ornithine-containing lipid Nalpha-(D)-[3-(hexadecanoyloxy)hexadecanoyl]-ornithine is a strong stimulant for macrophages and a useful adjuvant.
Kawai Y, Nakagawa Y, Matuyama T, Akagawa K, Itagawa K, Fukase K, Kusumoto S, Nishijima M, Yano I. Kawai Y, et al. Among authors: nishijima m. FEMS Immunol Med Microbiol. 1999 Jan;23(1):67-73. doi: 10.1111/j.1574-695X.1999.tb01718.x. FEMS Immunol Med Microbiol. 1999. PMID: 10030549 Free article.
Identification of a biochemical lesion, and characteristic response to lipopolysaccharide (LPS) of a cultured macrophage-like cell mutant with defective LPS-binding.
Nishijima M, Hara-Kuge S, Takasuka N, Akagawa K, Setouchi M, Matsuura K, Yamamoto S, Akamatsu Y. Nishijima M, et al. J Biochem. 1994 Nov;116(5):1082-7. doi: 10.1093/oxfordjournals.jbchem.a124631. J Biochem. 1994. PMID: 7534758 Free article.
This mutant had defective LPS binding [Hara-Kuge, S., Amano, F., Nishijima, M., and Akamatsu, Y. (1990) J. Biol. Chem. 265, 6606-6610]. In this study, we found that: (1) LPS-binding to parental J774.1 cells was dependent on a serum factor with a molecular weight of …
This mutant had defective LPS binding [Hara-Kuge, S., Amano, F., Nishijima, M., and Akamatsu, Y. (1990) J. Biol. Chem. 265, 66 …
Regulatory roles for MD-2 and TLR4 in ligand-induced receptor clustering.
Kobayashi M, Saitoh S, Tanimura N, Takahashi K, Kawasaki K, Nishijima M, Fujimoto Y, Fukase K, Akashi-Takamura S, Miyake K. Kobayashi M, et al. Among authors: nishijima m. J Immunol. 2006 May 15;176(10):6211-8. doi: 10.4049/jimmunol.176.10.6211. J Immunol. 2006. PMID: 16670331
550 results