Ryder TR - Search Results

1

N,N-dialkyl-dipeptidylamines as novel N-type calcium channel blockers.

Hu LY, Ryder TR, Rafferty MF, Cody WL, Lotarski SM, Miljanich GP, Millerman E, Rock DM, Song Y, Stoehr SJ, Taylor CP, Weber ML, Szoke BG, Vartanian MG. Hu LY, et al. Among authors: ryder tr. Bioorg Med Chem Lett. 1999 Mar 22;9(6):907-12. doi: 10.1016/s0960-894x(99)00100-6. Bioorg Med Chem Lett. 1999. PMID: 10206559

2

Synthesis and biological evaluation of substituted 4-(OBz)phenylalanine derivatives as novel N-type calcium channel blockers.

Hu LY, Ryder TR, Nikam SS, Millerman E, Szoke BG, Rafferty MF. Hu LY, et al. Among authors: ryder tr. Bioorg Med Chem Lett. 1999 Apr 19;9(8):1121-6. doi: 10.1016/s0960-894x(99)00160-2. Bioorg Med Chem Lett. 1999. PMID: 10328297

3

Multiple parallel synthesis of N,N-dialkyldipeptidylamines as N-type calcium channel blockers.

Ryder TR, Hu LY, Rafferty MF, Millerman E, Szoke BG, Tarczy-Hornoch K. Ryder TR, et al. Bioorg Med Chem Lett. 1999 Jul 5;9(13):1813-8. doi: 10.1016/s0960-894x(99)00284-x. Bioorg Med Chem Lett. 1999. PMID: 10406647

4

Structure-activity relationship of N-methyl-N-aralkyl-peptidylamines as novel N-type calcium channel blockers.

Hu LY, Ryder TR, Rafferty MF, Dooley DJ, Geer JJ, Lotarski SM, Miljanich GP, Millerman E, Rock DM, Stoehr SJ, Szoke BG, Taylor CP, Vartanian MG. Hu LY, et al. Among authors: ryder tr. Bioorg Med Chem Lett. 1999 Aug 2;9(15):2151-6. doi: 10.1016/s0960-894x(99)00359-5. Bioorg Med Chem Lett. 1999. PMID: 10465535

5

Structure-activity relationship at the proximal phenyl group in a series of non-peptidyl N-type calcium channel antagonists.

Ryder TR, Hu LY, Rafferty MF, Lotarski SM, Rock DM, Stoehr SJ, Taylor CP, Weber ML, Miljanich GP, Millerman E, Szoke BG. Ryder TR, et al. Bioorg Med Chem Lett. 1999 Aug 16;9(16):2453-8. doi: 10.1016/s0960-894x(99)00405-9. Bioorg Med Chem Lett. 1999. PMID: 10476886

6

Synthesis of a series of 4-benzyloxyaniline analogues as neuronal N-type calcium channel blockers with improved anticonvulsant and analgesic properties.

Hu LY, Ryder TR, Rafferty MF, Feng MR, Lotarski SM, Rock DM, Sinz M, Stoehr SJ, Taylor CP, Weber ML, Bowersox SS, Miljanich GP, Millerman E, Wang YX, Szoke BG. Hu LY, et al. Among authors: ryder tr. J Med Chem. 1999 Oct 7;42(20):4239-49. doi: 10.1021/jm9902739. J Med Chem. 1999. PMID: 10514294

7

Structure-activity relationship at the leucine side chain in a series of N,N-dialkyldipeptidyl-amines as N-type calcium channel blockers.

Ryder TR, Hu LY, Rafferty MF, Lotarski SM, Rock DM, Stoehr SJ, Taylor CP, Weber ML, Miljanich GP, Millerman E, Szoke BG. Ryder TR, et al. Drug Des Discov. 2000;16(4):317-22. Drug Des Discov. 2000. PMID: 10807036

8

The discovery of [1-(4-dimethylamino-benzyl)-piperidin-4-yl]-[4-(3,3-dimethylbutyl)-phen yl]-(3-methyl-but-2-enyl)-amine, an N-type Ca+2 channel blocker with oral activity for analgesia.

Hu LY, Ryder TR, Rafferty MF, Taylor CP, Feng MR, Kuo BS, Lotarski SM, Miljanich GP, Millerman E, Siebers KM, Szoke BG. Hu LY, et al. Among authors: ryder tr. Bioorg Med Chem. 2000 Jun;8(6):1203-12. doi: 10.1016/s0968-0896(00)00077-8. Bioorg Med Chem. 2000. PMID: 10896101

9

Neuronal N-type calcium channel blockers: a series of 4-piperidinylaniline analogs with analgesic activity.

Hu LY, Ryder TR, Rafferty MF, Siebers KM, Malone T, Chatterjee A, Feng MR, Lotarski SM, Rock DM, Stoehr SJ, Taylor CP, Weber ML, Miljanich GP, Millerman E, Szoke BG. Hu LY, et al. Among authors: ryder tr. Drug Des Discov. 2000;17(1):85-93. Drug Des Discov. 2000. PMID: 10928451

10

The design and synthesis of human branched-chain amino acid aminotransferase inhibitors for treatment of neurodegenerative diseases.

Hu LY, Boxer PA, Kesten SR, Lei HJ, Wustrow DJ, Moreland DW, Zhang L, Ahn K, Ryder TR, Liu X, Rubin JR, Fahnoe K, Carroll RT, Dutta S, Fahnoe DC, Probert AW, Roof RL, Rafferty MF, Kostlan CR, Scholten JD, Hood M, Ren XD, Schielke GP, Su TZ, Taylor CP, Mistry A, McConnell P, Hasemann C, Ohren J. Hu LY, et al. Among authors: ryder tr. Bioorg Med Chem Lett. 2006 May 1;16(9):2337-40. doi: 10.1016/j.bmcl.2005.07.058. Epub 2005 Sep 6. Bioorg Med Chem Lett. 2006. PMID: 16143519

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