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N,N-dialkyl-dipeptidylamines as novel N-type calcium channel blockers.
Hu LY, Ryder TR, Rafferty MF, Cody WL, Lotarski SM, Miljanich GP, Millerman E, Rock DM, Song Y, Stoehr SJ, Taylor CP, Weber ML, Szoke BG, Vartanian MG. Hu LY, et al. Among authors: stoehr sj. Bioorg Med Chem Lett. 1999 Mar 22;9(6):907-12. doi: 10.1016/s0960-894x(99)00100-6. Bioorg Med Chem Lett. 1999. PMID: 10206559
(S)-4-Methyl-2-(methylamino)pentanoic acid [4, 4-bis(4-fluorophenyl)butyl]amide hydrochloride, a novel calcium channel antagonist, is efficacious in several animal models of pain.
Song Y, Bowersox SS, Connor DT, Dooley DJ, Lotarski SM, Malone T, Miljanich G, Millerman E, Rafferty MF, Rock D, Roth BD, Schmidt J, Stoehr S, Szoke BG, Taylor C, Vartanian M, Wang YX. Song Y, et al. J Med Chem. 2000 Sep 21;43(19):3474-7. doi: 10.1021/jm000134n. J Med Chem. 2000. PMID: 11000000 No abstract available.
23 results