Giaccia AJ - Search Results

1

Mitogen-activated protein kinase phosphatase-1 (MKP-1) expression is induced by low oxygen conditions found in solid tumor microenvironments. A candidate MKP for the inactivation of hypoxia-inducible stress-activated protein kinase/c-Jun N-terminal protein kinase activity.

Laderoute KR, Mendonca HL, Calaoagan JM, Knapp AM, Giaccia AJ, Stork PJ. Laderoute KR, et al. Among authors: giaccia aj. J Biol Chem. 1999 Apr 30;274(18):12890-7. doi: 10.1074/jbc.274.18.12890. J Biol Chem. 1999. PMID: 10212278 Free article.

2

Activation of metallothionein gene expression by hypoxia involves metal response elements and metal transcription factor-1.

Murphy BJ, Andrews GK, Bittel D, Discher DJ, McCue J, Green CJ, Yanovsky M, Giaccia A, Sutherland RM, Laderoute KR, Webster KA. Murphy BJ, et al. Cancer Res. 1999 Mar 15;59(6):1315-22. Cancer Res. 1999. PMID: 10096565

3

Opposing effects of hypoxia on expression of the angiogenic inhibitor thrombospondin 1 and the angiogenic inducer vascular endothelial growth factor.

Laderoute KR, Alarcon RM, Brody MD, Calaoagan JM, Chen EY, Knapp AM, Yun Z, Denko NC, Giaccia AJ. Laderoute KR, et al. Among authors: giaccia aj. Clin Cancer Res. 2000 Jul;6(7):2941-50. Clin Cancer Res. 2000. PMID: 10914744

4

Oncogenic transformation and hypoxia synergistically act to modulate vascular endothelial growth factor expression.

Mazure NM, Chen EY, Yeh P, Laderoute KR, Giaccia AJ. Mazure NM, et al. Among authors: giaccia aj. Cancer Res. 1996 Aug 1;56(15):3436-40. Cancer Res. 1996. PMID: 8758908

5

Induction of vascular endothelial growth factor by hypoxia is modulated by a phosphatidylinositol 3-kinase/Akt signaling pathway in Ha-ras-transformed cells through a hypoxia inducible factor-1 transcriptional element.

Mazure NM, Chen EY, Laderoute KR, Giaccia AJ. Mazure NM, et al. Among authors: giaccia aj. Blood. 1997 Nov 1;90(9):3322-31. Blood. 1997. PMID: 9345014 Free article.

6

Epigenetic regulation of gene expression in cervical cancer cells by the tumor microenvironment.

Denko N, Schindler C, Koong A, Laderoute K, Green C, Giaccia A. Denko N, et al. Clin Cancer Res. 2000 Feb;6(2):480-7. Clin Cancer Res. 2000. PMID: 10690527

7

Protease inhibitor TPCK represses Ha-ras (Val12) transformation and nuclear factor-kappa B activation.

Denko N, Chen E, Laderoute K, Stambrook P, Giaccia A. Denko N, et al. Int J Oncol. 1997 May;10(5):895-900. doi: 10.3892/ijo.10.5.895. Int J Oncol. 1997. PMID: 21533459

8

Early responses of SiHa human squamous carcinoma cells to hypoxic signals.

Laderoute K, Calaoagan J, Mendonca H, Ausserer W, Chen E, Giaccia A, Sutherland R. Laderoute K, et al. Int J Oncol. 1996 May;8(5):875-82. doi: 10.3892/ijo.8.5.875. Int J Oncol. 1996. PMID: 21544440

9

ATR/ATM targets are phosphorylated by ATR in response to hypoxia and ATM in response to reoxygenation.

Hammond EM, Dorie MJ, Giaccia AJ. Hammond EM, et al. Among authors: giaccia aj. J Biol Chem. 2003 Apr 4;278(14):12207-13. doi: 10.1074/jbc.M212360200. Epub 2003 Jan 7. J Biol Chem. 2003. PMID: 12519769 Free article.

10

Heat shock protein 72 modulates pathways of stress-induced apoptosis.

Buzzard KA, Giaccia AJ, Killender M, Anderson RL. Buzzard KA, et al. Among authors: giaccia aj. J Biol Chem. 1998 Jul 3;273(27):17147-53. doi: 10.1074/jbc.273.27.17147. J Biol Chem. 1998. PMID: 9642282 Free article.

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