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Challenges and Opportunities in the Development of Medical Therapies for Pediatric Populations and the Role of Extrapolation.
Barrett JS, Bishai R, Bucci-Rechtweg C, Cheung A, Corriol-Rohou S, Haertter S, James A, Kovacs SJ, Liu J, Potempa D, Strougo A, Vanevski K; IQ consortium - CPLG Pediatric Working Group. Barrett JS, et al. Among authors: kovacs sj. Clin Pharmacol Ther. 2018 Mar;103(3):419-433. doi: 10.1002/cpt.1000. Epub 2018 Jan 31. Clin Pharmacol Ther. 2018. PMID: 29277892 Review.
Randomized, Open-Label Study of the Pharmacokinetics and Safety of Oral and Intravenous Administration of Omadacycline to Healthy Subjects.
Sun H, Ting L, Machineni S, Praestgaard J, Kuemmell A, Stein DS, Sunkara G, Kovacs SJ, Villano S, Tanaka SK. Sun H, et al. Among authors: kovacs sj. Antimicrob Agents Chemother. 2016 Nov 21;60(12):7431-7435. doi: 10.1128/AAC.01393-16. Print 2016 Dec. Antimicrob Agents Chemother. 2016. PMID: 27736760 Free PMC article. Clinical Trial.
Clinical disposition, metabolism and in vitro drug-drug interaction properties of omadacycline.
Flarakos J, Du Y, Gu H, Wang L, Einolf HJ, Chun DY, Zhu B, Alexander N, Natrillo A, Hanna I, Ting L, Zhou W, Dole K, Sun H, Kovacs SJ, Stein DS, Tanaka SK, Villano S, Mangold JB. Flarakos J, et al. Among authors: kovacs sj. Xenobiotica. 2017 Aug;47(8):682-696. doi: 10.1080/00498254.2016.1213465. Epub 2016 Aug 8. Xenobiotica. 2017. PMID: 27499331
134 results