McIntosh TS - Search Results

1

Morning spot and 24-hour urinary 6 beta-hydroxycortisol to cortisol ratios: intraindividual variability and correlation under basal conditions and conditions of CYP 3A4 induction.

Tran JQ, Kovacs SJ, McIntosh TS, Davis HM, Martin DE. Tran JQ, et al. Among authors: mcintosh ts. J Clin Pharmacol. 1999 May;39(5):487-94. J Clin Pharmacol. 1999. PMID: 10234596

2

A liquid chromatography-mass spectrometry method to measure stable isotopic tracer enrichments of glycerol and glucose in human serum.

McIntosh TS, Davis HM, Matthews DE. McIntosh TS, et al. Anal Biochem. 2002 Jan 15;300(2):163-9. doi: 10.1006/abio.2001.5455. Anal Biochem. 2002. PMID: 11779107

3

Utilizing pharmacokinetics/pharmacodynamics modeling to simultaneously examine free CCL2, total CCL2 and carlumab (CNTO 888) concentration time data.

Fetterly GJ, Aras U, Meholick PD, Takimoto C, Seetharam S, McIntosh T, de Bono JS, Sandhu SK, Tolcher A, Davis HM, Zhou H, Puchalski TA. Fetterly GJ, et al. J Clin Pharmacol. 2013 Oct;53(10):1020-7. doi: 10.1002/jcph.140. Epub 2013 Jul 23. J Clin Pharmacol. 2013. PMID: 23878055 Clinical Trial.

4

Mechanistic pharmacokinetic/target engagement/pharmacodynamic (PK/TE/PD) modeling in deciphering interplay between a monoclonal antibody and its soluble target in cynomolgus monkeys.

Wang W, Wang X, Doddareddy R, Fink D, McIntosh T, Davis HM, Zhou H. Wang W, et al. AAPS J. 2014 Jan;16(1):129-39. doi: 10.1208/s12248-013-9545-8. Epub 2013 Nov 28. AAPS J. 2014. PMID: 24287601 Free PMC article.

5

A novel approach to evaluate the pharmacokinetic biocomparability of a monoclonal antibody derived from two different cell lines using simultaneous crossover design.

Han C, McIntosh TS, Geist BJ, Jiao T, Puchalski TA, Goldberg KM, Yang TY, Pendley CE, Zhou H, Davis HM. Han C, et al. Among authors: mcintosh ts. AAPS J. 2014 Jan;16(1):125-8. doi: 10.1208/s12248-013-9547-6. Epub 2013 Nov 27. AAPS J. 2014. PMID: 24281691 Free PMC article.

6

A novel approach for the simultaneous quantification of a therapeutic monoclonal antibody in serum produced from two distinct host cell lines.

Geist BJ, Davis D, McIntosh T, Yang TY, Goldberg K, Han C, Pendley C, Davis HM. Geist BJ, et al. MAbs. 2013 Jan-Feb;5(1):150-61. doi: 10.4161/mabs.22773. Epub 2012 Nov 26. MAbs. 2013. PMID: 23182963 Free PMC article.

7

Normalization of skeletal muscle glycogen synthesis and glycolysis in rosiglitazone-treated Zucker fatty rats: an in vivo nuclear magnetic resonance study.

Jucker BM, Schaeffer TR, Haimbach RE, McIntosh TS, Chun D, Mayer M, Ohlstein DH, Davis HM, Smith SA, Cobitz AR, Sarkar SK. Jucker BM, et al. Among authors: mcintosh ts. Diabetes. 2002 Jul;51(7):2066-73. doi: 10.2337/diabetes.51.7.2066. Diabetes. 2002. PMID: 12086934

8

Development of different analysis platforms with LC-MS for pharmacokinetic studies of protein drugs.

Lu Q, Zheng X, McIntosh T, Davis H, Nemeth JF, Pendley C, Wu SL, Hancock WS. Lu Q, et al. Anal Chem. 2009 Nov 1;81(21):8715-23. doi: 10.1021/ac901991x. Anal Chem. 2009. PMID: 19788250 Free PMC article.

9

Development and Translational Application of a Minimal Physiologically Based Pharmacokinetic Model for a Monoclonal Antibody against Interleukin 23 (IL-23) in IL-23-Induced Psoriasis-Like Mice.

Chen X, Jiang X, Doddareddy R, Geist B, McIntosh T, Jusko WJ, Zhou H, Wang W. Chen X, et al. J Pharmacol Exp Ther. 2018 Apr;365(1):140-155. doi: 10.1124/jpet.117.244855. Epub 2018 Feb 2. J Pharmacol Exp Ther. 2018. PMID: 29420255

10

Deciphering the In Vivo Performance of a Monoclonal Antibody to Neutralize Its Soluble Target at the Site of Action in a Mouse Collagen-Induced Arthritis Model.

Wang W, McIntosh TS, Jiang X, Doddareddy R, Dell EC, Zhou H. Wang W, et al. Among authors: mcintosh ts. Pharm Res. 2016 Apr;33(4):1040-9. doi: 10.1007/s11095-015-1850-8. Epub 2015 Dec 30. Pharm Res. 2016. PMID: 26718954

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

16 results

Search Page

Filters