Bai R - Search Results

1

A new anti-tubulin agent containing the benzo[b]thiophene ring system.

Pinney KG, Bounds AD, Dingeman KM, Mocharla VP, Pettit GR, Bai R, Hamel E. Pinney KG, et al. Among authors: bai r. Bioorg Med Chem Lett. 1999 Apr 19;9(8):1081-6. doi: 10.1016/s0960-894x(99)00143-2. Bioorg Med Chem Lett. 1999. PMID: 10328289

2

Synthesis and biological evaluation of dihydrobenzofuran lignans and related compounds as potential antitumor agents that inhibit tubulin polymerization.

Pieters L, Van Dyck S, Gao M, Bai R, Hamel E, Vlietinck A, Lemière G. Pieters L, et al. Among authors: bai r. J Med Chem. 1999 Dec 30;42(26):5475-81. doi: 10.1021/jm990251m. J Med Chem. 1999. PMID: 10639289

3

Halichondrin B and homohalichondrin B, marine natural products binding in the vinca domain of tubulin. Discovery of tubulin-based mechanism of action by analysis of differential cytotoxicity data.

Bai RL, Paull KD, Herald CL, Malspeis L, Pettit GR, Hamel E. Bai RL, et al. J Biol Chem. 1991 Aug 25;266(24):15882-9. J Biol Chem. 1991. PMID: 1874739 Free article.

4

Binding of dolastatin 10 to tubulin at a distinct site for peptide antimitotic agents near the exchangeable nucleotide and vinca alkaloid sites.

Bai RL, Pettit GR, Hamel E. Bai RL, et al. J Biol Chem. 1990 Oct 5;265(28):17141-9. J Biol Chem. 1990. PMID: 2211617 Free article.

5

Structure-activity studies with chiral isomers and with segments of the antimitotic marine peptide dolastatin 10.

Bai RL, Pettit GR, Hamel E. Bai RL, et al. Biochem Pharmacol. 1990 Oct 15;40(8):1859-64. doi: 10.1016/0006-2952(90)90367-t. Biochem Pharmacol. 1990. PMID: 2242019

6

Dolastatin 15, a potent antimitotic depsipeptide derived from Dolabella auricularia. Interaction with tubulin and effects of cellular microtubules.

Bai R, Friedman SJ, Pettit GR, Hamel E. Bai R, et al. Biochem Pharmacol. 1992 Jun 23;43(12):2637-45. doi: 10.1016/0006-2952(92)90153-a. Biochem Pharmacol. 1992. PMID: 1632820

7

Antineoplastic agents 360. Synthesis and cancer cell growth inhibitory studies of dolastatin 15 structural modifications.

Pettit GR, Flahive EJ, Boyd MR, Bai R, Hamel E, Pettit RK, Schmidt JM. Pettit GR, et al. Among authors: bai r. Anticancer Drug Des. 1998 Jan;13(1):47-66. Anticancer Drug Des. 1998. PMID: 9474242

8

Antineoplastic agents 365. Dolastatin 10 SAR probes.

Pettit GR, Srirangam JK, Barkoczy J, Williams MD, Boyd MR, Hamel E, Pettit RK, Hogan F, Bai R, Chapuis JC, McAllister SC, Schmidt JM. Pettit GR, et al. Among authors: bai r. Anticancer Drug Des. 1998 Jun;13(4):243-77. Anticancer Drug Des. 1998. PMID: 9627667

9

Dolastatin 10, a powerful cytostatic peptide derived from a marine animal. Inhibition of tubulin polymerization mediated through the vinca alkaloid binding domain.

Bai R, Pettit GR, Hamel E. Bai R, et al. Biochem Pharmacol. 1990 Jun 15;39(12):1941-9. doi: 10.1016/0006-2952(90)90613-p. Biochem Pharmacol. 1990. PMID: 2353935

10

Differential effects of active isomers, segments, and analogs of dolastatin 10 on ligand interactions with tubulin. Correlation with cytotoxicity.

Bai R, Roach MC, Jayaram SK, Barkoczy J, Pettit GR, Ludueña RF, Hamel E. Bai R, et al. Biochem Pharmacol. 1993 Apr 6;45(7):1503-15. doi: 10.1016/0006-2952(93)90051-w. Biochem Pharmacol. 1993. PMID: 8471072

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