Nikam SS - Search Results

1

Synthesis and biological evaluation of substituted 4-(OBz)phenylalanine derivatives as novel N-type calcium channel blockers.

Hu LY, Ryder TR, Nikam SS, Millerman E, Szoke BG, Rafferty MF. Hu LY, et al. Among authors: nikam ss. Bioorg Med Chem Lett. 1999 Apr 19;9(8):1121-6. doi: 10.1016/s0960-894x(99)00160-2. Bioorg Med Chem Lett. 1999. PMID: 10328297

2

Design and synthesis of novel quinoxaline-2,3-dione AMPA/GlyN receptor antagonists: amino acid derivatives.

Nikam SS, Cordon JJ, Ortwine DF, Heimbach TH, Blackburn AC, Vartanian MG, Nelson CB, Schwarz RD, Boxer PA, Rafferty MF. Nikam SS, et al. J Med Chem. 1999 Jun 17;42(12):2266-71. doi: 10.1021/jm980455n. J Med Chem. 1999. PMID: 10377233

3

Subtype selective NMDA receptor antagonists: evaluation of some novel alkynyl analogues.

Kornberg BE, Nikam SS, Wright JL, Kesten SR, Meltzer LT, Coughenour L, Barr B, Serpa KA, McCormick J. Kornberg BE, et al. Among authors: nikam ss. Bioorg Med Chem Lett. 2004 Mar 8;14(5):1213-6. doi: 10.1016/j.bmcl.2003.12.049. Bioorg Med Chem Lett. 2004. PMID: 14980668

4

1-Aminoindanes as novel motif with potential atypical antipsychotic properties.

Graham JM, Coughenour LL, Barr BM, Rock DL, Nikam SS. Graham JM, et al. Among authors: nikam ss. Bioorg Med Chem Lett. 2008 Jan 15;18(2):489-93. doi: 10.1016/j.bmcl.2007.11.106. Epub 2007 Dec 3. Bioorg Med Chem Lett. 2008. PMID: 18160289

5

AMPA receptor antagonists.

Nikam SS, Kornberg BE. Nikam SS, et al. Curr Med Chem. 2001 Feb;8(2):155-70. doi: 10.2174/0929867013373877. Curr Med Chem. 2001. PMID: 11172672 Review.

6

Novel selective quinazoline inhibitors of endothelin converting enzyme-1.

Ahn K, Sisneros AM, Herman SB, Pan SM, Hupe D, Lee C, Nikam S, Cheng XM, Doherty AM, Schroeder RL, Haleen SJ, Kaw S, Emoto N, Yanagisawa M. Ahn K, et al. Biochem Biophys Res Commun. 1998 Feb 4;243(1):184-90. doi: 10.1006/bbrc.1998.8081. Biochem Biophys Res Commun. 1998. PMID: 9473502

7

Serotonergic properties of spiroxatrine enantiomers.

Nikam SS, Martin AR, Nelson DL. Nikam SS, et al. J Med Chem. 1988 Oct;31(10):1965-8. doi: 10.1021/jm00118a017. J Med Chem. 1988. PMID: 2902227

8

NR2B selective NMDA receptor antagonists.

Nikam SS, Meltzer LT. Nikam SS, et al. Curr Pharm Des. 2002;8(10):845-55. doi: 10.2174/1381612024607072. Curr Pharm Des. 2002. PMID: 11945135 Review.

9

Metabolism-dependent mutagenicity of a compound containing a piperazinyl indazole motif: Role of a novel p450-mediated metabolic reaction involving a putative oxaziridine intermediate.

Chen H, Murray J, Kornberg B, Dethloff L, Rock D, Nikam S, Mutlib AE. Chen H, et al. Chem Res Toxicol. 2006 Oct;19(10):1341-50. doi: 10.1021/tx050354+. Chem Res Toxicol. 2006. PMID: 17040103

10

3-arylimino-2-indolones are potent and selective galanin GAL3 receptor antagonists.

Konkel MJ, Lagu B, Boteju LW, Jimenez H, Noble S, Walker MW, Chandrasena G, Blackburn TP, Nikam SS, Wright JL, Kornberg BE, Gregory T, Pugsley TA, Akunne H, Zoski K, Wise LD. Konkel MJ, et al. Among authors: nikam ss. J Med Chem. 2006 Jun 29;49(13):3757-8. doi: 10.1021/jm060001n. J Med Chem. 2006. PMID: 16789730

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