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Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: identification of 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benze nesulfonamide (SC-58635, celecoxib).
Penning TD, Talley JJ, Bertenshaw SR, Carter JS, Collins PW, Docter S, Graneto MJ, Lee LF, Malecha JW, Miyashiro JM, Rogers RS, Rogier DJ, Yu SS, AndersonGD, Burton EG, Cogburn JN, Gregory SA, Koboldt CM, Perkins WE, Seibert K, Veenhuizen AW, Zhang YY, Isakson PC. Penning TD, et al. Among authors: carter js. J Med Chem. 1997 Apr 25;40(9):1347-65. doi: 10.1021/jm960803q. J Med Chem. 1997. PMID: 9135032
4,5-Diaryloxazole inhibitors of cyclooxygenase-2 (COX-2).
Talley JJ, Bertenshaw SR, Brown DL, Carter JS, Graneto MJ, Koboldt CM, Masferrer JL, Norman BH, Rogier DJ Jr, Zwwifel BS, Seibert K. Talley JJ, et al. Among authors: carter js. Med Res Rev. 1999 May;19(3):199-208. doi: 10.1002/(sici)1098-1128(199905)19:3<199::aid-med1>3.0.co;2-7. Med Res Rev. 1999. PMID: 10232649 Review.
Mechanism of inhibition of novel COX-2 inhibitors.
Gierse J, Kurumbail R, Walker M, Hood B, Monahan J, Pawlitz J, Stegeman R, Stevens A, Kiefer J, Koboldt C, Moreland K, Rowlinson S, Marnett L, Pierce J, Carter J, Talley J, Isakson P, Seibert K. Gierse J, et al. Adv Exp Med Biol. 2002;507:365-9. doi: 10.1007/978-1-4615-0193-0_56. Adv Exp Med Biol. 2002. PMID: 12664611 No abstract available.
111 results