Cushman M - Search Results

1

Extension of the polyanionic cosalane pharmacophore as a strategy for increasing anti-HIV potency.

Cushman M, Insaf S, Paul G, Ruell JA, De Clercq E, Schols D, Pannecouque C, Witvrouw M, Schaeffer CA, Turpin JA, Williamson K, Rice WG. Cushman M, et al. J Med Chem. 1999 May 20;42(10):1767-77. doi: 10.1021/jm980727m. J Med Chem. 1999. PMID: 10346929

2

Synthesis and evaluation of analogues of (Z)-1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene as potential cytotoxic and antimitotic agents.

Cushman M, Nagarathnam D, Gopal D, He HM, Lin CM, Hamel E. Cushman M, et al. J Med Chem. 1992 Jun 12;35(12):2293-306. doi: 10.1021/jm00090a021. J Med Chem. 1992. PMID: 1613753

3

Preparation and anti-HIV activities of aurintricarboxylic acid fractions and analogues: direct correlation of antiviral potency with molecular weight.

Cushman M, Wang PL, Chang SH, Wild C, De Clercq E, Schols D, Goldman ME, Bowen JA. Cushman M, et al. J Med Chem. 1991 Jan;34(1):329-37. doi: 10.1021/jm00105a052. J Med Chem. 1991. PMID: 1704065

4

Synthesis and anti-HIV activities of low molecular weight aurintricarboxylic acid fragments and related compounds.

Cushman M, Kanamathareddy S, De Clercq E, Schols D, Goldman ME, Bowen JA. Cushman M, et al. J Med Chem. 1991 Jan;34(1):337-42. doi: 10.1021/jm00105a053. J Med Chem. 1991. PMID: 1704066

5

Synthesis and evaluation of stilbene and dihydrostilbene derivatives as potential anticancer agents that inhibit tubulin polymerization.

Cushman M, Nagarathnam D, Gopal D, Chakraborti AK, Lin CM, Hamel E. Cushman M, et al. J Med Chem. 1991 Aug;34(8):2579-88. doi: 10.1021/jm00112a036. J Med Chem. 1991. PMID: 1875350

6

Synthesis and protein-tyrosine kinase inhibitory activities of flavonoid analogues.

Cushman M, Nagarathnam D, Burg DL, Geahlen RL. Cushman M, et al. J Med Chem. 1991 Feb;34(2):798-806. doi: 10.1021/jm00106a047. J Med Chem. 1991. PMID: 1995903

7

Synthesis and cytotoxicity of water-soluble ambrosin prodrug candidates.

Hejchman E, Haugwitz RD, Cushman M. Hejchman E, et al. Among authors: cushman m. J Med Chem. 1995 Aug 18;38(17):3407-10. doi: 10.1021/jm00017a025. J Med Chem. 1995. PMID: 7650694

8

Synthesis, antitubulin and antimitotic activity, and cytotoxicity of analogs of 2-methoxyestradiol, an endogenous mammalian metabolite of estradiol that inhibits tubulin polymerization by binding to the colchicine binding site.

Cushman M, He HM, Katzenellenbogen JA, Lin CM, Hamel E. Cushman M, et al. J Med Chem. 1995 Jun 9;38(12):2041-9. doi: 10.1021/jm00012a003. J Med Chem. 1995. PMID: 7783135

9

Cosalane analogues with enhanced potencies as inhibitors of HIV-1 protease and integrase.

Cushman M, Golebiewski WM, Pommier Y, Mazumder A, Reymen D, De Clercq E, Graham L, Rice WG. Cushman M, et al. J Med Chem. 1995 Feb 3;38(3):443-52. doi: 10.1021/jm00003a007. J Med Chem. 1995. PMID: 7853337

10

Design, synthesis, and biological evaluation of cosalane, a novel anti-HIV agent which inhibits multiple features of virus reproduction.

Cushman M, Golebiewski WM, McMahon JB, Buckheit RW Jr, Clanton DJ, Weislow O, Haugwitz RD, Bader JP, Graham L, Rice WG. Cushman M, et al. J Med Chem. 1994 Sep 16;37(19):3040-50. doi: 10.1021/jm00045a008. J Med Chem. 1994. PMID: 7932526

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