Hoogenboom HR - Search Results

1

A large non-immunized human Fab fragment phage library that permits rapid isolation and kinetic analysis of high affinity antibodies.

de Haard HJ, van Neer N, Reurs A, Hufton SE, Roovers RC, Henderikx P, de Bruïne AP, Arends JW, Hoogenboom HR. de Haard HJ, et al. Among authors: hoogenboom hr. J Biol Chem. 1999 Jun 25;274(26):18218-30. doi: 10.1074/jbc.274.26.18218. J Biol Chem. 1999. PMID: 10373423 Free article.

2

Antibody phage display technology and its applications.

Hoogenboom HR, de Bruïne AP, Hufton SE, Hoet RM, Arends JW, Roovers RC. Hoogenboom HR, et al. Immunotechnology. 1998 Jun;4(1):1-20. doi: 10.1016/s1380-2933(98)00007-4. Immunotechnology. 1998. PMID: 9661810 Review.

3

High-affinity recombinant phage antibodies to the pan-carcinoma marker epithelial glycoprotein-2 for tumour targeting.

Roovers RC, Henderikx P, Helfrich W, van der Linden E, Reurs A, de Bruïne AP, Arends JW, de Leij L, Hoogenboom HR. Roovers RC, et al. Among authors: hoogenboom hr. Br J Cancer. 1998 Dec;78(11):1407-16. doi: 10.1038/bjc.1998.700. Br J Cancer. 1998. PMID: 9836471 Free PMC article.

4

Selection of phage-displayed fab antibodies on the active conformation of ras yields a high affinity conformation-specific antibody preventing the binding of c-Raf kinase to Ras.

Horn IR, Wittinghofer A, de Bruïne AP, Hoogenboom HR. Horn IR, et al. Among authors: hoogenboom hr. FEBS Lett. 1999 Dec 10;463(1-2):115-20. doi: 10.1016/s0014-5793(99)01617-8. FEBS Lett. 1999. PMID: 10601649 Free article.

5

Phage display of cDNA repertoires: the pVI display system and its applications for the selection of immunogenic ligands.

Hufton SE, Moerkerk PT, Meulemans EV, de Bruïne A, Arends JW, Hoogenboom HR. Hufton SE, et al. Among authors: hoogenboom hr. J Immunol Methods. 1999 Dec 10;231(1-2):39-51. doi: 10.1016/s0022-1759(99)00139-8. J Immunol Methods. 1999. PMID: 10648926

6

Model systems to study the parameters determining the success of phage antibody selections on complex antigens.

Mutuberria R, Hoogenboom HR, van der Linden E, de Bruïne AP, Roovers RC. Mutuberria R, et al. Among authors: hoogenboom hr. J Immunol Methods. 1999 Dec 10;231(1-2):65-81. doi: 10.1016/s0022-1759(99)00141-6. J Immunol Methods. 1999. PMID: 10648928

7

Guided selection of a pan carcinoma specific antibody reveals similar binding characteristics yet structural divergence between the original murine antibody and its human equivalent.

Beiboer SH, Reurs A, Roovers RC, Arends JW, Whitelegg NR, Rees AR, Hoogenboom HR. Beiboer SH, et al. Among authors: hoogenboom hr. J Mol Biol. 2000 Feb 25;296(3):833-49. doi: 10.1006/jmbi.2000.3512. J Mol Biol. 2000. PMID: 10677285

8

Direct selection of a human antibody fragment directed against the tumor T-cell epitope HLA-A1-MAGE-A1 from a nonimmunized phage-Fab library.

Chames P, Hufton SE, Coulie PG, Uchanska-Ziegler B, Hoogenboom HR. Chames P, et al. Among authors: hoogenboom hr. Proc Natl Acad Sci U S A. 2000 Jul 5;97(14):7969-74. doi: 10.1073/pnas.97.14.7969. Proc Natl Acad Sci U S A. 2000. PMID: 10884427 Free PMC article.

9

In vitro characterisation of a monovalent and bivalent form of a fully human anti Ep-CAM phage antibody.

Roovers RC, van der Linden E, de Bruïne AP, Arends JW, Hoogenboom HR. Roovers RC, et al. Among authors: hoogenboom hr. Cancer Immunol Immunother. 2001 Mar;50(1):51-9. doi: 10.1007/s002620000160. Cancer Immunol Immunother. 2001. PMID: 11315510 Free PMC article.

10

Selection of antibodies against biotinylated antigens.

Chames P, Hoogenboom HR, Henderikx P. Chames P, et al. Among authors: hoogenboom hr. Methods Mol Biol. 2002;178:147-57. doi: 10.1385/1-59259-240-6:147. Methods Mol Biol. 2002. PMID: 11968483 Review. No abstract available.

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