Nowotnik DP - Search Results

1

Multi-institutional, randomized, double-blind, placebo-controlled trial to assess the efficacy of a mucoadhesive hydrogel (MuGard) in mitigating oral mucositis symptoms in patients being treated with chemoradiation therapy for cancers of the head and neck.

Allison RR, Ambrad AA, Arshoun Y, Carmel RJ, Ciuba DF, Feldman E, Finkelstein SE, Gandhavadi R, Heron DE, Lane SC, Longo JM, Meakin C, Papadopoulos D, Pruitt DE, Steinbrenner LM, Taylor MA, Wisbeck WM, Yuh GE, Nowotnik DP, Sonis ST. Allison RR, et al. Among authors: nowotnik dp. Cancer. 2014 May 1;120(9):1433-40. doi: 10.1002/cncr.28553. Cancer. 2014. PMID: 24877167 Free PMC article. Clinical Trial.

2

ProLindac (AP5346): a review of the development of an HPMA DACH platinum Polymer Therapeutic.

Nowotnik DP, Cvitkovic E. Nowotnik DP, et al. Adv Drug Deliv Rev. 2009 Nov 12;61(13):1214-9. doi: 10.1016/j.addr.2009.06.004. Epub 2009 Aug 9. Adv Drug Deliv Rev. 2009. PMID: 19671439 Review.

3

Phase I and pharmacokinetic trial of AP5346, a DACH-platinum-polymer conjugate, administered weekly for three out of every 4 weeks to advanced solid tumor patients.

Campone M, Rademaker-Lakhai JM, Bennouna J, Howell SB, Nowotnik DP, Beijnen JH, Schellens JH. Campone M, et al. Among authors: nowotnik dp. Cancer Chemother Pharmacol. 2007 Sep;60(4):523-33. doi: 10.1007/s00280-006-0397-0. Epub 2007 Feb 17. Cancer Chemother Pharmacol. 2007. PMID: 17308894 Clinical Trial.

4

Synthesis and characterization of AP5346, a novel polymer-linked diaminocyclohexyl platinum chemotherapeutic agent.

Sood P, Thurmond KB 2nd, Jacob JE, Waller LK, Silva GO, Stewart DR, Nowotnik DP. Sood P, et al. Among authors: nowotnik dp. Bioconjug Chem. 2006 Sep-Oct;17(5):1270-9. doi: 10.1021/bc0600517. Bioconjug Chem. 2006. PMID: 16984138

5

Preclinical efficacy and pharmacokinetics of AP5346, a novel diaminocyclohexane-platinum tumor-targeting drug delivery system.

Rice JR, Gerberich JL, Nowotnik DP, Howell SB. Rice JR, et al. Among authors: nowotnik dp. Clin Cancer Res. 2006 Apr 1;12(7 Pt 1):2248-54. doi: 10.1158/1078-0432.CCR-05-2169. Clin Cancer Res. 2006. PMID: 16609041

6

Improved targeting of platinum chemotherapeutics. the antitumour activity of the HPMA copolymer platinum agent AP5280 in murine tumour models.

Lin X, Zhang Q, Rice JR, Stewart DR, Nowotnik DP, Howell SB. Lin X, et al. Among authors: nowotnik dp. Eur J Cancer. 2004 Jan;40(2):291-7. doi: 10.1016/j.ejca.2003.09.022. Eur J Cancer. 2004. PMID: 14728945

7

Pharmaceutical development of a parenteral lyophilized formulation of the investigational polymer-conjugated platinum anticancer agent AP 5280.

Bouma M, Nuijen B, Harms R, Rice JR, Nowotnik DP, Stewart DR, Jansen BA, van Zutphen S, Reedijk J, van Steenbergen MJ, Talsma H, Bult A, Beijnen JH. Bouma M, et al. Among authors: nowotnik dp. Drug Dev Ind Pharm. 2003 Oct;29(9):981-95. doi: 10.1081/ddc-120025455. Drug Dev Ind Pharm. 2003. PMID: 14606662

8

Technetium(V) oxo complexes of substituted propylene diamine dioxime (PnAO) ligands: water-dependent interconversion between syn and anti isomers.

Cyr JE, Nowotnik DP, Pan Y, Gougoutas JZ, Malley MF, Di Marco J, Nunn AD, Linder KE. Cyr JE, et al. Among authors: nowotnik dp. Inorg Chem. 2001 Jul 2;40(14):3555-61. doi: 10.1021/ic991381o. Inorg Chem. 2001. PMID: 11421705

9

Dopamine transporter loss and clinical changes in MPTP-lesioned primates.

Eberling JL, Bankiewicz KS, Pivirotto P, Bringas J, Chen K, Nowotnik DP, Steiner JP, Budinger TF, Jagust WJ. Eberling JL, et al. Among authors: nowotnik dp. Brain Res. 1999 Jun 19;832(1-2):184-7. doi: 10.1016/s0006-8993(99)01491-2. Brain Res. 1999. PMID: 10375668

10

Delineation of the border zone of ischemic rabbit myocardium by a technetium-labeled nitroimidazole.

Di Rocco RJ, Bauer AA, Pirro JP, Kuczynski BL, Belnavis L, Chan YW, Linder KE, Narra RK, Nowotnik DP, Nunn AD. Di Rocco RJ, et al. Among authors: nowotnik dp. Nucl Med Biol. 1997 Apr;24(3):201-7. doi: 10.1016/0969-8051(95)02035-7. Nucl Med Biol. 1997. PMID: 9228654

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