Park JS - Search Results

1

Radiation-induced release of transforming growth factor alpha activates the epidermal growth factor receptor and mitogen-activated protein kinase pathway in carcinoma cells, leading to increased proliferation and protection from radiation-induced cell death.

Dent P, Reardon DB, Park JS, Bowers G, Logsdon C, Valerie K, Schmidt-Ullrich R. Dent P, et al. Among authors: park js. Mol Biol Cell. 1999 Aug;10(8):2493-506. doi: 10.1091/mbc.10.8.2493. Mol Biol Cell. 1999. PMID: 10436007 Free PMC article.

2

Roles for basal and stimulated p21(Cip-1/WAF1/MDA6) expression and mitogen-activated protein kinase signaling in radiation-induced cell cycle checkpoint control in carcinoma cells.

Park JS, Carter S, Reardon DB, Schmidt-Ullrich R, Dent P, Fisher PB. Park JS, et al. Mol Biol Cell. 1999 Dec;10(12):4231-46. doi: 10.1091/mbc.10.12.4231. Mol Biol Cell. 1999. PMID: 10588655 Free PMC article.

3

Ionizing radiation-induced mitogen-activated protein (MAP) kinase activation in DU145 prostate carcinoma cells: MAP kinase inhibition enhances radiation-induced cell killing and G2/M-phase arrest.

Hagan M, Wang L, Hanley JR, Park JS, Dent P. Hagan M, et al. Among authors: park js. Radiat Res. 2000 Apr;153(4):371-83. doi: 10.1667/0033-7587(2000)153[0371:irimap]2.0.co;2. Radiat Res. 2000. PMID: 10760996

4

A role for both Ets and C/EBP transcription factors and mRNA stabilization in the MAPK-dependent increase in p21 (Cip-1/WAF1/mda6) protein levels in primary hepatocytes.

Park JS, Qiao L, Gilfor D, Yang MY, Hylemon PB, Benz C, Darlington G, Firestone G, Fisher PB, Dent P. Park JS, et al. Mol Biol Cell. 2000 Sep;11(9):2915-32. doi: 10.1091/mbc.11.9.2915. Mol Biol Cell. 2000. PMID: 10982390 Free PMC article.

5

Pharmocologic inhibitors of the mitogen activated protein kinase cascade have the potential to interact with ionizing radiation exposure to induce cell death in carcinoma cells by multiple mechanisms.

Qiao L, Yacoub A, McKinstry R, Park JS, Caron R, Fisher PB, Hagan MP, Grant S, Dent P. Qiao L, et al. Among authors: park js. Cancer Biol Ther. 2002 Mar-Apr;1(2):168-76. doi: 10.4161/cbt.64. Cancer Biol Ther. 2002. PMID: 12170777 Free article.

6

Bile acid regulation of C/EBPbeta, CREB, and c-Jun function, via the extracellular signal-regulated kinase and c-Jun NH2-terminal kinase pathways, modulates the apoptotic response of hepatocytes.

Qiao L, Han SI, Fang Y, Park JS, Gupta S, Gilfor D, Amorino G, Valerie K, Sealy L, Engelhardt JF, Grant S, Hylemon PB, Dent P. Qiao L, et al. Among authors: park js. Mol Cell Biol. 2003 May;23(9):3052-66. doi: 10.1128/MCB.23.9.3052-3066.2003. Mol Cell Biol. 2003. PMID: 12697808 Free PMC article.

7

Prolonged activation of the mitogen-activated protein kinase pathway promotes DNA synthesis in primary hepatocytes from p21Cip-1/WAF1-null mice, but not in hepatocytes from p16INK4a-null mice.

Auer KL, Park JS, Seth P, Coffey RJ, Darlington G, Abo A, McMahon M, Depinho RA, Fisher PB, Dent P. Auer KL, et al. Among authors: park js. Biochem J. 1998 Dec 15;336 ( Pt 3)(Pt 3):551-60. doi: 10.1042/bj3360551. Biochem J. 1998. PMID: 9841865 Free PMC article.

8

Inhibition of the mitogen activated protein kinase pathway potentiates radiation-induced cell killing via cell cycle arrest at the G2/M transition and independently of increased signaling by the JNK/c-Jun pathway.

Cartee L, Vrana JA, Wang Z, Park JS, Birrer M, Fisher PB, Grant S, Dent P. Cartee L, et al. Among authors: park js. Int J Oncol. 2000 Feb;16(2):413-22. Int J Oncol. 2000. PMID: 10639586

9

Ionizing radiation modulates vascular endothelial growth factor (VEGF) expression through multiple mitogen activated protein kinase dependent pathways.

Park JS, Qiao L, Su ZZ, Hinman D, Willoughby K, McKinstry R, Yacoub A, Duigou GJ, Young CS, Grant S, Hagan MP, Ellis E, Fisher PB, Dent P. Park JS, et al. Oncogene. 2001 May 31;20(25):3266-80. doi: 10.1038/sj.onc.1204258. Oncogene. 2001. PMID: 11423976

10

Hepatitis B virus X protein increases expression of p21(Cip-1/WAF1/MDA6) and p27(Kip-1) in primary mouse hepatocytes, leading to reduced cell cycle progression.

Qiao L, Leach K, McKinstry R, Gilfor D, Yacoub A, Park JS, Grant S, Hylemon PB, Fisher PB, Dent P. Qiao L, et al. Among authors: park js. Hepatology. 2001 Nov;34(5):906-17. doi: 10.1053/jhep.2001.28886. Hepatology. 2001. PMID: 11679961

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