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Although DR3-DQB1*0201 may be associated with multiple component diseases of the autoimmune polyglandular syndromes, the human leukocyte antigen DR4-DQB1*0302 haplotype is implicated only in beta-cell autoimmunity.
Huang W, Connor E, Rosa TD, Muir A, Schatz D, Silverstein J, Crockett S, She JX, Maclaren NK. Huang W, et al. Among authors: schatz d. J Clin Endocrinol Metab. 1996 Jul;81(7):2559-63. doi: 10.1210/jcem.81.7.8675578. J Clin Endocrinol Metab. 1996. PMID: 8675578
Only multiple autoantibodies to islet cells (ICA), insulin, GAD65, IA-2 and IA-2beta predict immune-mediated (Type 1) diabetes in relatives.
Maclaren N, Lan M, Coutant R, Schatz D, Silverstein J, Muir A, Clare-Salzer M, She JX, Malone J, Crockett S, Schwartz S, Quattrin T, DeSilva M, Vander Vegt P, Notkins A, Krischer J. Maclaren N, et al. Among authors: schatz d. J Autoimmun. 1999 Jun;12(4):279-87. doi: 10.1006/jaut.1999.0281. J Autoimmun. 1999. PMID: 10330299
Aberrant monocyte prostaglandin synthase 2 (PGS2) expression in type 1 diabetes before and after disease onset.
Litherland SA, She JX, Schatz D, Fuller K, Hutson AD, Peng RH, Li Y, Grebe KM, Whittaker DS, Bahjat K, Hopkins D, Fang Q, Spies PD, North K, Wasserfall C, Cook R, Dennis MA, Crockett S, Sleasman J, Kocher J, Muir A, Silverstein J, Atkinson M, Clare-Salzler MJ. Litherland SA, et al. Among authors: schatz d. Pediatr Diabetes. 2003 Mar;4(1):10-8. doi: 10.1034/j.1399-5448.2003.00042.x. Pediatr Diabetes. 2003. PMID: 14655518
High frequency of abnormal glucose tolerance in DQA1*0102/DQB1*0602 relatives identified as part of the Diabetes Prevention Trial--Type 1 Diabetes.
Greenbaum CJ, Eisenbarth G, Atkinson M, Yu L, Babu S, Schatz D, Zeidler A, Orban T, Wasserfall C, Cuthbertson D, Krischer J; DPT-1 study group. Greenbaum CJ, et al. Among authors: schatz d. Diabetologia. 2005 Jan;48(1):68-74. doi: 10.1007/s00125-004-1608-z. Epub 2004 Dec 16. Diabetologia. 2005. PMID: 15602651
761 results